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Genotoxic effect of high nitrate water consumption in men and woman from northern Mar del plata, Argentina JBAG
Poli,M.N; López Miranda,L.A; Fernández Iriarte,P.J; Zanier,G.J; Iúdica,C.E.
Previous research has shown connections between the exposure to different agents and mutations in germinal and somatic cells. One of such agents, nitrate (NO3), can be potentially genotoxic for individuals who drink high nitrate well water, and may cause a subsequent impact on their health and on the whole ecosystem. The aim of this research was to conduct genotoxicity assays in somatic cells from people living in the northern area of Mar del Plata city, Argentina. The purpose of these experiments was, in turn, to establish the possible relationships between mutagenic effects and high nitrate water consumption. To this end, different diagnostic tests were carried out to detect potential genetic and/or chromosomal alterations. A non-exposed population equal...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Mutagenic agents; Nitrate; Chromosomal aberrations; Genotoxicity; Micronuclei.
Ano: 2012 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1852-62332012000100001
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Survival and mutant production induced by mutagenic agents in Metarhizium anisopliae Scientia Agricola
Kava - Cordeiro,V.; Luna - Alves - Lima,E.A.; Azevedo,J.L..
A wild strain of Metarhizium anisopliae, an entomopathogenic fungus, was submitted to three mutagenic agents: gamma radiation, ultraviolet light and nitrous acid. Survival curves were obtained and mutants were selected using different mutagenic doses which gave 1 to 5% survival. Morphological and auxotrophic mutants were isolated. Morphological mutants were grouped in a class with yellow conidia and other with pale vinaceous conidia as opposed to the green wild type conidia. Auxotrophic mutants had requirements for vitamin and aminoacid biosynthesis. More than 58% of the total auxotrophk mutants required proline/aipnine. Gamma radiation showed to be the most efficient mutagenic agent giving 0.2% of auxotrophk mutants followed by ultraviolet light (0.12%)...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Metarhizium anisopliae; Auxotrophk mutants; Colour mutants; Mutagenic agents; Gamma radiation; Ultraviolet light; Nitrous acid.
Ano: 1995 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90161995000300023
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